EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.2.1.35 | hyaluronan + 2 H2O | Homo sapiens | - |
N-acetyl-beta-D-glucosamine + D-glucuronate + ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.212 | Homo sapiens | Q92839 | isoform HAS1 | - |
3.2.1.35 | Homo sapiens | Q12794 | - |
- |
3.2.1.35 | Homo sapiens | Q12891 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.1.212 | HT-1080 cell | - |
Homo sapiens | - |
3.2.1.35 | HT-1080 cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.2.1.35 | hyaluronan + 2 H2O | - |
Homo sapiens | N-acetyl-beta-D-glucosamine + D-glucuronate + ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.2.1.35 | HYAL1 | isoform | Homo sapiens |
3.2.1.35 | Hyal2 | isoform | Homo sapiens |
3.2.1.35 | hyaluronidase-1 | isoform | Homo sapiens |
3.2.1.35 | hyaluronidase-2 | isoform | Homo sapiens |
EC Number | Organism | Comment | Expression |
---|---|---|---|
2.4.1.212 | Homo sapiens | basic fibroblast growth factor bFGF increases HA-synthase-1 and -2 expression and enhances high molecular weight hyaluronan deposition in the pericellular matrix | up |
3.2.1.35 | Homo sapiens | basic fibroblast growth factor decreases hyaluronidase-2 expression in HT-1080 cells | down |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.4.1.212 | physiological function | mainly high molecular weight hyaluronan synthesized by isoform HAS1 regulates HT-1080 cell motility | Homo sapiens |