Literature summary extracted from

Cunningham, P.R.; Weitzmann, C.J.; Nurse, K.; Masurel, R.; van Knippenberg, P.H.; Ofengand, J.
Site-specific mutation of the conserved m6(2)A m6(2)A residues of E. coli 16S ribosomal RNA. Effects on ribosome function and activity of the ksgA methyltransferase (1990), Biochim. Biophys. Acta, 1050, 18-26.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.1.182	Escherichia coli	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.1.1.182	4 S-adenosyl-L-methionine + adenine1518/adenine1519 in 16S rRNA	neither of the adenine residues is required for methylation of the other, ruling out any obligate order of methylation of A1518 and A1519. Mutation of either A1518 or A1519 to C, G or U has little effect on the ability of the mutant RNA to reconstitute a 30S ribosome containing a full complement of ribosomal proteins	Escherichia coli	4 S-adenosyl-L-homocysteine + N6-dimethyladenine1518/N6-dimethyladenine1519 in 16S rRNA	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.1.1.182	ksgA methyltransferase	-	Escherichia coli

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Release 2023.1 (January 2023)