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Literature summary extracted from
- Base excision repair in early zebrafish development: evidence for DNA polymerase switching and standby AP endonuclease activity (2009), Biochemistry, 48, 5396-5404.
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.99.18 | Danio rerio | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.2.99.18 | adult | - |
Danio rerio | - |
| 4.2.99.18 | egg | - |
Danio rerio | - |
| 4.2.99.18 | embryo | - |
Danio rerio | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.99.18 | DNA | - |
Danio rerio | fragments of DNA | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.2.99.18 | AP endonuclease 1 | - |
Danio rerio |
| 4.2.99.18 | ZAP1 | - |
Danio rerio |
Expression
| EC Number | Organism | Comment | Expression |
|---|---|---|---|
| 4.2.99.18 | Danio rerio | the level of ZAP1 is reduced by 74-90% by microinjection of 0.5 mM morpholino oligonucleotides directed against the translation start site at the 2-4 cell stage | down |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 4.2.99.18 | malfunction | knockdown of ZAP1 levels does not alter base excision repair in early embryogenesis | Danio rerio |
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Release 2023.1 (January 2023)
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