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Literature summary extracted from

  • Hays Putnam, A.M.; Lee, Y.T.; Goodin, D.B.
    Replacement of an electron transfer pathway in cytochrome c peroxidase with a surrogate peptide (2009), Biochemistry, 48, 1-3.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.11.1.5 expression in Escherichia coli Saccharomyces cerevisiae

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.11.1.5 protein channel mutant with surrogate protein (N-benzimidazole-propionic acid)-Gly-Ala-Ala (BzGAA), vapor diffusion, 200 mM KPi, 25% MPD, pH 6.0, temperature 282K, space group P212121, resolution 1.6 A Saccharomyces cerevisiae

Protein Variants

EC Number Protein Variants Comment Organism
1.11.1.5 additional information variant of cytochrome c peroxidase in which the proposed electron transfer pathway is excised from the structure, leaving a water filled channel in its place Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.11.1.5 cytochrome c + H2O2 Saccharomyces cerevisiae
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.5 Saccharomyces cerevisiae P00431 bakerย’s yeast
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.5 cytochrome c + H2O2
-
 Saccharomyces cerevisiae ?
-
 ?
1.11.1.5 additional information investigation of an engineered channel mutant with the surrogate peptide (N-benzimidazole-propionic acid)-Gly-Ala-Ala (BzGAA), complete loss of functional activity in the BzGAA/ET channel mutant strongly supports proposals that the Trp-191 radical intermediate is required for efficient turnover of cyt c via the proposed ET pathway Saccharomyces cerevisiae ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.11.1.5 CCP
-
 Saccharomyces cerevisiae
1.11.1.5 cytochrome c peroxidase
-
 Saccharomyces cerevisiae

General Information

EC Number General Information Comment Organism
1.11.1.5 physiological function electron transfer Saccharomyces cerevisiae