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Literature summary extracted from

  • Huang, L.; Ku, J.; Pookanjanatavip, M.; Gu, X.; Wang, D.; Greene, P.J.; Santi, D.V.
    Identification of two Escherichia coli pseudouridine synthases that show multisite specificity for 23S RNA (1998), Biochemistry, 37, 15951-15957.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.4.99.23 overexpressed in Escherichia coli Escherichia coli
5.4.99.24 overexpressed in Escherichia coli Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.4.99.23 23S rRNA uridine1911/uridine1915/uridine1917 Escherichia coli
-
 23S rRNA pseudouridine1911/pseudouridine1915/pseudouridine1917
-
 ?
5.4.99.24 23S rRNA uridine955/uridine2504/uridine2580 Escherichia coli
-
 23S rRNA pseudouridine955/pseudouridine2504/pseudouridine2580
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.4.99.23 Escherichia coli
-
-
-
5.4.99.24 Escherichia coli
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.4.99.23
-
 Escherichia coli
5.4.99.24
-
 Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.99.23 23S rRNA uridine1911/uridine1915/uridine1917
-
 Escherichia coli 23S rRNA pseudouridine1911/pseudouridine1915/pseudouridine1917
-
 ?
5.4.99.24 23S rRNA uridine955/uridine2504/uridine2580
-
 Escherichia coli 23S rRNA pseudouridine955/pseudouridine2504/pseudouridine2580
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.4.99.23 YfiI
-
 Escherichia coli
5.4.99.24 YceC
-
 Escherichia coli

General Information

EC Number General Information Comment Organism
5.4.99.23 malfunction yfiI-disrupted cells show a dramatic decrease in growth rate Escherichia coli
5.4.99.24 malfunction disruption of yceC does not affect the growth Escherichia coli