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Literature summary extracted from

  • Sharov, V.S.; Galeva, N.A.; Dremina, E.S.; Williams, T.D.; Schoeneich, C.
    Inactivation of rabbit muscle glycogen phosphorylase b by peroxynitrite revisited: does the nitration of Tyr613 in the allosteric inhibition site control enzymatic function? (2009), Arch. Biochem. Biophys., 484, 155-166.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.1 peroxynitrite 1 mM, almost complete inactivation. After the exposure to 1 mM peroxynitrite, the molar content of Cys residues decreases from 8.63 to 3.43 and 4.24 in the absence and in the presence of bicarbonate, respectively. The addition of 1 mM DTT in 10 min after peroxynitrite treatment does not significantly reverse loss of either activity or molar content of DTNB-reactive Cys residues. No involvement of Tyr613 nitration in the control of enzymatic function. The enzymatic activity does not directly correlate with the protein nitration levels Oryctolagus cuniculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.1 97000
-
 x * 97000, SDS-PAGE Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.1 Oryctolagus cuniculus P00489 glycogen phosphorylase b
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.1 muscle
-
 Oryctolagus cuniculus
-

Subunits

EC Number Subunits Comment Organism
2.4.1.1 ? x * 97000, SDS-PAGE Oryctolagus cuniculus