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Literature summary extracted from

  • Lue, Z.R.; Oh, S.H.; Zhou, S.S.; Zou, H.C.; Park, D.; Park, S.J.; Zhou, H.W.; Bhak, J.; Park, Y.D.; Zou, F.
    Structural analysis and inhibitory Kinetics of brain type creatine kinase by sodium dodecyl sulfate (2010), Appl. Biochem. Biotechnol., 160, 831-842.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.3.2 SDS strongly inhibits the CK-BB activity in a noncompetitive manner, although almost all the activity is eliminated by SDS CK-BB is never completely inactivated (4% to 5% activity is still sustained), regardless of increased incubation time or SDS concentration Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.3.2 cytoplasm
-
 Homo sapiens 5737
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.3.2 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.3.2 brain
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.3.2 ATP + creatine
-
 Homo sapiens ADP + creatine phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.3.2 homodimer
-
 Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.7.3.2 ATP: creatine N-phosphotransferase
-
 Homo sapiens
2.7.3.2 brain creatine kinase
-
 Homo sapiens
2.7.3.2 CK-BB
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.3.2 ATP
-
 Homo sapiens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.7.3.2 1.22
-
 SDS in 5 mM glycine-NaOH (pH 9.0), at 25°C Homo sapiens