Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Jiang, S.S.; Liu, M.C.; Teng, L.J.; Wang, W.B.; Hsueh, P.R.; Liaw, S.J.
    Proteus mirabilis pmrI, an RppA-regulated gene necessary for polymyxin B resistance, biofilm formation, and urothelial cell invasion (2010), Antimicrob. Agents Chemother., 54, 1564-1571.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.1.35 expression in Escherichia coli BL21 as His-tagged enzyme Proteus mirabilis

Protein Variants

EC Number Protein Variants Comment Organism
4.1.1.35 additional information by using Tn5 transposon mutagenesis, a gene, PpmrI, is identified which plays important roles in controlling lipopolysaccharides modification, polymyxin B susceptibility, biofilm formation, and cell invasion in Proteus mirabilis. The expression of PpmrI can be induced by polymyxin B via RppA, a response regulator of the bacterial two-component system. Together, these results reveal a mechanism by which Proteus mirabilis regulates polymyxin B resistance and virulence Proteus mirabilis

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.35 Proteus mirabilis C9E3L0
-
-
4.1.1.35 Proteus mirabilis N2 C9E3L0
-
-

Synonyms

EC Number Synonyms Comment Organism
4.1.1.35 UDP-glucuronic acid decarboxylase
-
 Proteus mirabilis

Expression

EC Number Organism Comment Expression
4.1.1.35 Proteus mirabilis expression of PpmrI can be induced by polymyxin B via RppA, a response regulator of the bacterial two-component system. Together, these results reveal a mechanism by which Proteus mirabilis regulates polymyxin B resistance and virulence up