EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.5.1.3 | BAL0030543 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Staphylococcus aureus | |
1.5.1.3 | BAL0030543 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Streptococcus mitis | |
1.5.1.3 | BAL0030543 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Streptococcus pneumoniae | |
1.5.1.3 | BAL0030544 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Staphylococcus aureus | |
1.5.1.3 | BAL0030544 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Streptococcus mitis | |
1.5.1.3 | BAL0030544 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Streptococcus pneumoniae | |
1.5.1.3 | BAL0030545 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Staphylococcus aureus | |
1.5.1.3 | BAL0030545 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Streptococcus mitis | |
1.5.1.3 | BAL0030545 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Streptococcus pneumoniae | |
1.5.1.3 | trimethoprim | - |
Staphylococcus aureus | |
1.5.1.3 | trimethoprim | - |
Streptococcus mitis | |
1.5.1.3 | trimethoprim | - |
Streptococcus pneumoniae |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.5.1.3 | Staphylococcus aureus | - |
methicillin-sensitive and -resistant strains | - |
1.5.1.3 | Streptococcus mitis | - |
methicillin-sensitive and -resistant strains | - |
1.5.1.3 | Streptococcus pneumoniae | - |
methicillin-sensitive and -resistant strains | - |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.5.1.3 | DHFR | - |
Staphylococcus aureus |
1.5.1.3 | DHFR | - |
Streptococcus pneumoniae |
1.5.1.3 | DHFR | - |
Streptococcus mitis |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.5.1.3 | physiological function | dihydrofolate reductase is an enzyme with a pivotal role in the synthesis of intracellular tetrahydrofolic acid, which is essential in the synthesis of purines, some amino acids, and thymidine. DHFR is the sole source of tetrahydrofolic acid | Staphylococcus aureus |
1.5.1.3 | physiological function | dihydrofolate reductase is an enzyme with a pivotal role in the synthesis of intracellular tetrahydrofolic acid, which is essential in the synthesis of purines, some amino acids, and thymidine. DHFR is the sole source of tetrahydrofolic acid | Streptococcus pneumoniae |
1.5.1.3 | physiological function | dihydrofolate reductase is an enzyme with a pivotal role in the synthesis of intracellular tetrahydrofolic acid, which is essential in the synthesis of purines, some amino acids, and thymidine. DHFR is the sole source of tetrahydrofolic acid | Streptococcus mitis |