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Literature summary extracted from

  • Abdel Aziz, M.T.; Mostafa, T.; Roshdy, N.; Hosni, H.; Rashed, L.; Sabry, D.; Abdel Nasser, T.; Abdel Azim, O.; Abdel Gawad, O.
    Heme oxygenase enzyme activity in human seminal plasma of fertile and infertile males (2008), Andrologia, 40, 292-297.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.14.14.18 additional information positive correlation between seminal plasma HO enzyme activity and sperm concentration, sperm motility percentage, motile spermatozoa ml-1 and sperm normal morphology per cent Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.18 Homo sapiens
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-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.18 seminal plasma activity is very low in obstructive azoospermia specimens, low in nonobstructive azoospermia, moderate in oligozoospermia while higher in normozoospermia. HO-2 expression in all studied groups whereas HO-1 is highly expressed in fertile normozoospermic group compared with other groups Homo sapiens
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.18 heme + electron donor + O2
-
Homo sapiens biliverdin + Fe2+ + CO + oxidized electron donor + H2O
-
?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.18 heme oxygenase
-
Homo sapiens
1.14.14.18 HO-1
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Homo sapiens
1.14.14.18 HO-2
-
Homo sapiens

General Information

EC Number General Information Comment Organism
1.14.14.18 physiological function HO enzyme activity in the human seminal plasma is related to spermatogenesis and sperm-motility processes Homo sapiens