Literature summary extracted from

Morin, C.; Guibert, C.; Sirois, M.; Echave, V.; Gomes, M.M.; Rousseau, E.
Effects of omega-hydroxylase product on distal human pulmonary arteries (2008), Am. J. Physiol. Heart Circ. Physiol., 294, H1435-H1443.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.14.15.3	N-methylsulfonyl-12,12-dibromododec-11-enamide	specific inhibitor, results in an increased phenylephrine-induced tension	Homo sapiens

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.14.15.3	52000	-	Western blot analysis	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.15.3	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.14.15.3	pulmonary artery	distal	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.15.3	arachidonic acid + NAD(P)H + H+ + O2	product formation relaxes distal human pulmonary arteries	Homo sapiens	(5Z,8Z,11Z,14Z)-20-hydroxyeicosa-5,8,11,14-tetraenoic acid + NAD(P)+ + H2O	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.14.15.3	CYP450 4A omega-hydroxylase	-	Homo sapiens
1.14.15.3	CYP4A	-	Homo sapiens
1.14.15.3	cytochrome P-450 omega-hydroxylase	-	Homo sapiens
1.14.15.3	omega-hydroxylase	-	Homo sapiens

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Release 2023.1 (January 2023)