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Literature summary extracted from

  • de la Motte, C.; Nigro, J.; Vasanji, A.; Rho, H.; Kessler, S.; Bandyopadhyay, S.; Danese, S.; Fiocchi, C.; Stern, R.
    Platelet-derived hyaluronidase 2 cleaves hyaluronan into fragments that trigger monocyte-mediated production of proinflammatory cytokines (2009), Am. J. Pathol., 174, 2254-2264.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.35 hyaluronan + 2 H2O Homo sapiens
-
 N-acetyl-beta-D-glucosamine + D-glucuronate + ?
-
 ?
3.2.1.35 hyaluronan + 2 H2O Mus musculus
-
 N-acetyl-beta-D-glucosamine + D-glucuronate + ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.35 Homo sapiens Q12891
-
-
3.2.1.35 Mus musculus O35632
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.35 blood platelet contains only HYAL2 but not HYAL1 Homo sapiens
-
3.2.1.35 blood platelet contains only HYAL2 but not HYAL1 Mus musculus
-
3.2.1.35 megakaryocyte contains only HYAL2 but not HYAL1 Homo sapiens
-
3.2.1.35 megakaryocyte contains only HYAL2 but not HYAL1 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.35 hyaluronan + 2 H2O
-
 Homo sapiens N-acetyl-beta-D-glucosamine + D-glucuronate + ?
-
 ?
3.2.1.35 hyaluronan + 2 H2O
-
 Mus musculus N-acetyl-beta-D-glucosamine + D-glucuronate + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.35 Hyal2
-
 Homo sapiens
3.2.1.35 Hyal2
-
 Mus musculus
3.2.1.35 hyaluronidase 2
-
 Homo sapiens
3.2.1.35 hyaluronidase 2
-
 Mus musculus