Literature summary extracted from

Minchenko, D.O.; Mykhalchenko, V.G.; Tsuchihara, K.; Kanehara, S.; Yavorovsky, O.P.; Zaygorodny, I.V.; Paustovsky, Y.O.; Komisarenko, S.V.; Esumi, H.; Minchenko, O.H.
Alternative splice variants of rat 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4 mRNA (2008), Ukr. Biokhim. Zh., 80, 66-73.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.1.3.46	additional information	a significant decrease of isoform PFKFB-4 mRNA expression is found in the lung from rats treated by methyl tretbutyl ether during two months; a significant decrease of isoform PFKFB-4 mRNA expression is found in the lung from rats treated by methyl tretbutyl ether during two months	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.3.46	Rattus norvegicus	B0ZTI0	splice variant	-
3.1.3.46	Rattus norvegicus	P25114	splice variant	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.1.3.46	liver	-	Rattus norvegicus	-
3.1.3.46	lung	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.1.3.46	beta-D-fructose 2,6-bisphosphate + H2O	-	Rattus norvegicus	D-fructose 6-phosphate + phosphate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.1.3.46	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4	-	Rattus norvegicus
3.1.3.46	PFKFB-4	isoform, bifunctional enzyme	Rattus norvegicus

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Release 2023.1 (January 2023)