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Literature summary extracted from

  • Keating, A.F.; Rajapaksa, K.S.; Sipes, I.G.; Hoyer, P.B.
    Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure (2008), Toxicol. Sci., 105, 351-359.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.3.2.9 additional information 4-vinylcyclohexene diepoxide (0.005 mM) causes an increase in mEH mRNA by 0.5fold at day 10 Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.3.2.9 microsome
-
 Mus musculus
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.3.2.9 50000
-
 SDS-PAGE Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
3.3.2.9 Mus musculus
-
-
-
3.3.2.9 Mus musculus 129S1/SvImJ
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.3.2.9 ovarian follicle
-
 Mus musculus
-
3.3.2.9 ovary
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.3.2.9 4-vinylcyclohexene diepoxide + H2O
-
 Mus musculus 4-(1,2-dihydroxy)ethyl-1,2-dihydroxycyclohexane
-
 ?
3.3.2.9 4-vinylcyclohexene diepoxide + H2O
-
 Mus musculus 129S1/SvImJ 4-(1,2-dihydroxy)ethyl-1,2-dihydroxycyclohexane
-
 ?
3.3.2.9 cis-stilbene oxide + H2O
-
 Mus musculus (1R,2R)-1,2-diphenylethane-1,2-diol
-
 ?
3.3.2.9 cis-stilbene oxide + H2O
-
 Mus musculus 129S1/SvImJ (1R,2R)-1,2-diphenylethane-1,2-diol
-
 ?
3.3.2.9 cytochrome P450 isoform 1B1 + H2O
-
 Mus musculus 7,12-dimethylbenz(a)anthracene-3,4-diol
-
 ?
3.3.2.9 cytochrome P450 isoform 1B1 + H2O
-
 Mus musculus 129S1/SvImJ 7,12-dimethylbenz(a)anthracene-3,4-diol
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.3.2.9 mEH
-
 Mus musculus