EC Number | Application | Comment | Organism |
---|---|---|---|
1.3.8.8 | medicine | the developed LC-MS/MS method is able to provide ample sensitivity to correctly and rapidly determine MCAD and VLCAD residual activity in human lymphocytes | Homo sapiens |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
1.3.8.8 | A985G | nearly all patients with residual MCAD activities below 2.5% are homozygous 985A>G carriers | Homo sapiens |
1.3.8.8 | T199C | all patients with the 199T>C mutation have residual activities above 10% | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.3.8.8 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.3.8.8 | lymphocyte | - |
Homo sapiens | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.3.8.8 | additional information | - |
heterozygous ACADVL mutation carriers show residual VLCAD activities of 23.7 to 54.2% | Homo sapiens |
1.3.8.8 | additional information | - |
residual VLCAD activity of patients with confirmed VLCAD-deficiency is between 0.3 and 1.1% | Homo sapiens |
1.3.8.8 | 0.00238 | - |
MCAD activity, controls | Homo sapiens |
1.3.8.8 | 0.00695 | - |
VLCAD activity, controls, range 0.00195 to 0.01191 | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.8.8 | octanoyl-CoA + acceptor | MCAD activity assay | Homo sapiens | ? | - |
? | |
1.3.8.8 | palmitoleoyl-CoA + acceptor | VLCAD activity assay | Homo sapiens | ? | - |
? | |
1.3.8.8 | palmitoyl-CoA + acceptor | VLCAD activity assay | Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.3.8.8 | LCAD | - |
Homo sapiens |
1.3.8.8 | long-chain acyl-CoA dehydrogenase | - |
Homo sapiens |
1.3.8.8 | MCAD | - |
Homo sapiens |
1.3.8.8 | medium long-chain acyl-CoA dehydrogenase | - |
Homo sapiens |
1.3.8.8 | very long-chain acyl-CoA dehydrogenase | - |
Homo sapiens |
1.3.8.8 | VLCAD | - |
Homo sapiens |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.3.8.8 | 37 | - |
activity assay | Homo sapiens |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.3.8.8 | 8 | - |
activity assay | Homo sapiens |