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Literature summary extracted from

  • Retamal, P.; Castillo-Ruiz, M.; Mora, G.C.
    Characterization of MgtC, a virulence factor of Salmonella enterica Serovar Typhi (2009), PLoS ONE, 4, e5551.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
7.2.2.14 additional information low Mg2+ concentration, acidic media and the PhoP regulator induce mgtC expression in Salmonella enterica serovar Typhi Salmonella enterica

Cloned(Commentary)

EC Number Cloned (Comment) Organism
7.2.2.14 gene mgtC is encoded in the pathogenicity island 3, SPI-3 Salmonella enterica

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.2.2.14 ATP + H2O + Mg2+/out Salmonella enterica the MgtC is a virulence factor in Salmonella Typhimurium that is required for growth at low Mg2+ concentrations and intramacrophage survival ADP + phosphate + Mg2+/in
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Organism

EC Number Organism UniProt Comment Textmining
7.2.2.14 Salmonella enterica
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serovar Typhi, a Chilean clinical isolate of the human specific pathogen
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.2.2.14 ATP + H2O + Mg2+/out
-
Salmonella enterica ADP + phosphate + Mg2+/in
-
?
7.2.2.14 ATP + H2O + Mg2+/out the MgtC is a virulence factor in Salmonella Typhimurium that is required for growth at low Mg2+ concentrations and intramacrophage survival Salmonella enterica ADP + phosphate + Mg2+/in
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?

Subunits

EC Number Subunits Comment Organism
7.2.2.14 More MgtC epitope tagging, overview Salmonella enterica

Synonyms

EC Number Synonyms Comment Organism
7.2.2.14 MgtC
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Salmonella enterica

Cofactor

EC Number Cofactor Comment Organism Structure
7.2.2.14 ATP
-
Salmonella enterica