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Literature summary extracted from

  • Baxter, I.; Muthukumar, B.; Park, H.C.; Buchner, P.; Lahner, B.; Danku, J.; Zhao, K.; Lee, J.; Hawkesford, M.J.; Guerinot, M.L.; Salt, D.E.
    Variation in molybdenum content across broadly distributed populations of Arabidopsis thaliana is controlled by a mitochondrial molybdenum transporter (MOT1) (2008), PLoS Genet., 4, e1000004.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
7.3.2.5 genotyping, expression in protoplast mitochondrial membranes as GFP-tagged protein, quantitative expression analysis by realtime PCR, expression of MOT1 specifically enhances molybdenum accumulation in Saccharomyces cerevisiae by 5fold Arabidopsis thaliana

Protein Variants

EC Number Protein Variants Comment Organism
7.3.2.5 additional information a naturally occuring deletion mutation in the MOT1 promoter, leading to the mutants Ler-0 and Van-0, is strongly associated with low shoot molybdenum, occurring in seven of the accessions with the lowest shoot content of molybdenum. Consistent with the low molybdenum phenotype, MOT1 expression in low molybednum accessions is reduced, phenotype, overview Arabidopsis thaliana

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.3.2.5 mitochondrial membrane MOT1 contains an N-terminal mitochondrial targeting sequence Arabidopsis thaliana 31966
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.3.2.5 ATP + H2O + molybdate/out Arabidopsis thaliana
-
 ADP + phosphate + molybdate/in
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.3.2.5 Arabidopsis thaliana
-
 cv. Col-0
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.3.2.5 hypocotyl
-
 Arabidopsis thaliana
-
7.3.2.5 leaf
-
 Arabidopsis thaliana
-
7.3.2.5 root high expression level, expression in the protodermal cells behind the root tip, and in epidermis and cortex at the elongation zone Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.3.2.5 ATP + H2O + molybdate/out
-
 Arabidopsis thaliana ADP + phosphate + molybdate/in
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.3.2.5 mitochondrial molybdenum transporter
-
 Arabidopsis thaliana
7.3.2.5 molybdenum tansporter 1
-
 Arabidopsis thaliana
7.3.2.5 More the enzyme belongs to the sulfate transporter superfamily of enzyme Arabidopsis thaliana
7.3.2.5 MOT1
-
 Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
7.3.2.5 ATP
-
 Arabidopsis thaliana