Literature summary extracted from

McHugh, P.C.; Joyce, P.R.; Kennedy, M.R.
Polymorphisms of sepiapterin reductase gene alter promoter activity and may influence risk of bipolar disorder (2009), Pharmacogenet. Genomics, 19, 330-337.

Application

EC Number	Application	Comment	Organism
1.1.1.153	medicine	polymorphisms of sepiapterin reductase gene alter promoter activity and may influence risk of bipolar disorder	Homo sapiens

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.1.1.153	expressed in COS-7 and RNA-64A cells	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.153	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.1.1.153	blood	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.153	6-pyruvoyl tetrahydropterin + 2 NADPH + 2 H+	-	Homo sapiens	tetrahydrobiopterin + NADP+	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.1.1.153	SPR	-	Homo sapiens

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.1.1.153	NADPH	-	Homo sapiens

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Release 2023.1 (January 2023)