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Literature summary extracted from

  • McHugh, P.C.; Joyce, P.R.; Kennedy, M.R.
    Polymorphisms of sepiapterin reductase gene alter promoter activity and may influence risk of bipolar disorder (2009), Pharmacogenet. Genomics, 19, 330-337.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.1.1.153 medicine polymorphisms of sepiapterin reductase gene alter promoter activity and may influence risk of bipolar disorder Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.153 expressed in COS-7 and RNA-64A cells Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.153 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.153 blood
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.153 6-pyruvoyl tetrahydropterin + 2 NADPH + 2 H+
-
 Homo sapiens tetrahydrobiopterin + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.153 SPR
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.153 NADPH
-
 Homo sapiens