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Literature summary extracted from

  • Togawa, H.; Nakanishi, K.; Shima, Y.; Obana, M.; Sako, M.; Nozu, K.; Tanaka, R.; Iijima, K.; Yoshikawa, N.
    Increased chymase-positive mast cells in children with crescentic glomerulonephritis (2009), Pediatr. Nephrol., 24, 1071-1075.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.21.39 additional information chymase has no enzymatic activity under normal physiological conditions, but it is activated immediately after release into the extracellular matrix Homo sapiens

Application

EC Number Application Comment Organism
3.4.21.39 medicine mast cell-derived chymase plays an important role in juvenile crescentic glomerulonephritis Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.39 angiotensin I + H2O Homo sapiens
-
 angiotensin II + His-Leu
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.39 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.39 kidney
-
 Homo sapiens
-
3.4.21.39 mast cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.39 angiotensin I + H2O
-
 Homo sapiens angiotensin II + His-Leu
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.39 mast cell-derived chymase
-
 Homo sapiens
3.4.21.39 MC-derived chymase
-
 Homo sapiens