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Literature summary extracted from

  • Zrenner, R.; Riegler, H.; Marquard, C.R.; Lange, P.R.; Geserick, C.; Bartosz, C.E.; Chen, C.T.; Slocum, R.D.
    A functional analysis of the pyrimidine catabolic pathway in Arabidopsis (2009), New Phytol., 183, 117-132.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.1.6 expression of GFP-tagged PYD3 in Arabdiopsis thaliana via Agrobacterium-mediated transformation using the floral dip method. Quantitative real-time RT-PCR analysis of PYD expression in wild-type and pyd mutants, overview Arabidopsis thaliana

Protein Variants

EC Number Protein Variants Comment Organism
3.5.1.6 additional information construction of a T-DNA knockout mutant of gene PYD3, the mutant exhibits no obvious phenotype under optimal growing conditions, but the pyd3 mutant is unable to catabolize [2-14C]-uracil or to grow on uracil as the sole nitrogen source Arabidopsis thaliana

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.5.1.6 cytosol
-
Arabidopsis thaliana 5829
-
3.5.2.2 secretory granule
-
Arabidopsis thaliana 30141
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.1.6 N-carbamoyl-beta-alanine + H2O Arabidopsis thaliana
-
beta-alanine + CO2 + NH3
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.6 Arabidopsis thaliana Q8H183
-
-
3.5.2.2 Arabidopsis thaliana
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.1.6 seedling expression anaylsis, overview Arabidopsis thaliana
-
3.5.2.2 mesophyll
-
Arabidopsis thaliana
-
3.5.2.2 seedling
-
Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.6 N-carbamoyl-beta-alanine + H2O
-
Arabidopsis thaliana beta-alanine + CO2 + NH3
-
?
3.5.2.2 5,6-dihydrouracil + H2O
-
Arabidopsis thaliana N-carbamoyl-beta-alanine
-
?

Synonyms

EC Number Synonyms Comment Organism
3.5.1.6 beta-ureidopropionase
-
Arabidopsis thaliana
3.5.1.6 PYD3
-
Arabidopsis thaliana
3.5.2.2 DHPase
-
Arabidopsis thaliana
3.5.2.2 PYD2
-
Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
3.5.1.6 metabolism PYD3 is involved in the reductive pathway for the degradation of pyrimidine nucleotides, functional and mutational analysis of the catabolic pathway, overview Arabidopsis thaliana