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Literature summary extracted from

  • Oien, D.B.; Osterhaus, G.L.; Lundquist, B.L.; Fowler, S.C.; Moskovitz, J.
    Caloric restriction alleviates abnormal locomotor activity and dopamine levels in the brain of the methionine sulfoxide reductase A knockout mouse (2010), Neurosci. Lett., 468, 38-41.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
1.8.4.11 Mus musculus Q9D6Y7
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-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.4.11 brain
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Mus musculus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.4.11 L-methionine (S)-sulfoxide + 2 dithiothreitol
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Mus musculus L-methionine + dithiothreitol disulfide + H2O
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?

Synonyms

EC Number Synonyms Comment Organism
1.8.4.11 methionine sulfoxide reductase A
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Mus musculus
1.8.4.11 MsrA
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Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.4.11 dithiothreitol
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Mus musculus

General Information

EC Number General Information Comment Organism
1.8.4.11 physiological function MsrA knockout mice exhibit altered locomotor activity and brain dopamine levels as function of age, caloric restriction has a neutralization effect on MsrA ablation Mus musculus