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Literature summary extracted from

  • Nithitanakool, S.; Pithayanukul, P.; Bavovada, R.; Saparpakorn, P.
    Molecular docking studies and anti-tyrosinase activity of Thai mango seed kernel extract (2009), Molecules, 14, 257-265.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.18.1 gallic acid shows a concentration-dependent inhibitory activity against tyrosinase with IC50 of 0.644 mg/ml Agaricus bisporus
1.14.18.1 kojic acid IC50 of 0.0021 mg/ml Agaricus bisporus
1.14.18.1 methyl gallate shows a concentration-dependent inhibitory activity against tyrosinase with IC50 of 0.0625 mg/ml Agaricus bisporus
1.14.18.1 additional information the alcoholic extract from seed kernels of Thai mango (Mangifera indica L. cultivar Fahlun) exhibits potent, dose-dependent inhibitory effect on tyrosinase with respect to L-DOPA with IC50 of 0.09863 mg/ml Agaricus bisporus
1.14.18.1 pentagalloyl glucopyranose exhibits potent, dose-dependent inhibitory effect on tyrosinase with respect to L-DOPA with IC50 of 0.04265 mg/ml Agaricus bisporus

Organism

EC Number Organism UniProt Comment Textmining
1.14.18.1 Agaricus bisporus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.18.1 L-tyrosine + O2
-
 Agaricus bisporus dopaquinone + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.18.1 tyrosinase
-
 Agaricus bisporus