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Literature summary extracted from

  • Kohlstedt, K.; Gershome, C.; Trouvain, C.; Hofmann, W.K.; Fichtlscherer, S.; Fleming, I.
    Angiotensin-converting enzyme (ACE) inhibitors modulate cellular retinol-binding protein 1 and adiponectin expression in adipocytes via the ACE-dependent signaling cascade (2009), Mol. Pharmacol., 75, 685-692.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.15.1 expressed in 3T3-L1 cells Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
3.4.15.1 S1270A nonphosphorylatable signaling-dead ACE mutant Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.15.1 ramipril
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.15.1 angiotensin I + H2O Homo sapiens
-
 angiotensin II + L-His-L-Leu
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.15.1 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.15.1 adipocyte
-
 Homo sapiens
-
3.4.15.1 HUVEC cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.15.1 angiotensin I + H2O
-
 Homo sapiens angiotensin II + L-His-L-Leu
-
 ?
3.4.15.1 hippuryl-L-His-L-Leu + H2O
-
 Homo sapiens hippuric acid + L-His-L-Leu
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.15.1 ACE
-
 Homo sapiens
3.4.15.1 angiotensin-converting enzyme
-
 Homo sapiens