Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Wu, B.; Chen, J.; Qu, H.; Cheng, Y.
    Complex sesquiterpenoids with tyrosinase inhibitory activity from the leaves of Chloranthus tianmushanensis (2008), J. Nat. Prod., 71, 877-880.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.18.1 8-O-methyltianmushanol
-
Agaricus bisporus
1.14.18.1 kojic acid
-
Agaricus bisporus
1.14.18.1 additional information atractylenolide III, isofuranodiene, glechomanolide, and chloranthalactone A exhibit no inhibition against tyrosinase Agaricus bisporus
1.14.18.1 tianmushanol
-
Agaricus bisporus

Organism

EC Number Organism UniProt Comment Textmining
1.14.18.1 Agaricus bisporus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.18.1 L-DOPA + O2
-
Agaricus bisporus dopaquinone + H2O
-
?

Synonyms

EC Number Synonyms Comment Organism
1.14.18.1 tyrosinase
-
Agaricus bisporus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.14.18.1 0.243
-
in 50 mM Na-phosphate buffer (pH 6.8), at 37°C Agaricus bisporus kojic acid
1.14.18.1 0.312
-
in 50 mM Na-phosphate buffer (pH 6.8), at 37°C Agaricus bisporus 8-O-methyltianmushanol
1.14.18.1 0.358
-
in 50 mM Na-phosphate buffer (pH 6.8), at 37°C Agaricus bisporus tianmushanol