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Literature summary extracted from

  • Popowska, M.; Kusio, M.; Szymanska, P.; Markiewicz, Z.
    Inactivation of the wall-associated de-N-acetylase (PgdA) of Listeria monocytogenes results in greater susceptibility of the cells to induced autolysis (2009), J. Microbiol. Biotechnol., 19, 932-945.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.5.1.104 cell wall
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 Listeria monocytogenes 5618
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.1.104 peptidoglycan-N-acetyl-D-glucosamine + H2O Listeria monocytogenes peptidoglycan N-deacetylation is an important modification of Listeria peptidoglycan, which allows this human pathogen to evade the innate immune system peptidoglycan-D-glucosamine + acetate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.104 Listeria monocytogenes
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.1.104 hexa-His-tagged form of PgdA Listeria monocytogenes

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.104 additional information N-acetylmuramic acid is not a substrate. With N-acetylglucosamine as substrate D-glucosamine is formed Listeria monocytogenes ?
-
 ?
3.5.1.104 peptidoglycan-N-acetyl-D-glucosamine + H2O peptidoglycan N-deacetylation is an important modification of Listeria peptidoglycan, which allows this human pathogen to evade the innate immune system Listeria monocytogenes peptidoglycan-D-glucosamine + acetate
-
 ?
3.5.1.104 peptidoglycan-N-acetyl-D-glucosamine + H2O N-acetylated murein after lysozyme digestion Listeria monocytogenes peptidoglycan-D-glucosamine + acetate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.1.104 Lmo0415
-
 Listeria monocytogenes
3.5.1.104 peptidoglycan N-acetylglucosamine deacetylase
-
 Listeria monocytogenes
3.5.1.104 pgdA
-
 Listeria monocytogenes

General Information

EC Number General Information Comment Organism
3.5.1.104 malfunction inactivation of the wall-associated de-N-acetylase results in greater susceptibility of the cells to induced autolysis Listeria monocytogenes
3.5.1.104 physiological function peptidoglycan N-deacetylation is an important modification of Listeria peptidoglycan, which allows this human pathogen to evade the innate immune system Listeria monocytogenes