EC Number | Application | Comment | Organism |
---|---|---|---|
2.5.1.78 | medicine | this protein constitutes an interesting candidate for serological diagnosis and for the design of specific chemotherapeutic agents, and its polymeric characteristics could provide the basis for the development of an acellular vaccine | Brucella sp. |
EC Number | Cloned (Comment) | Organism |
---|---|---|
2.5.1.78 | expression in Escherichia coli. The recombinant protein is soluble only under reducing conditions, but alkylation with iodoacetamide renders it soluble in non-reducing media | Brucella sp. |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.5.1.78 | cytoplasm | - |
Brucella sp. | 5737 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.5.1.78 | 18000 | - |
x * 18000, SDS-PAGE | Brucella sp. |
2.5.1.78 | 90000 | - |
gel filtration | Brucella sp. |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.5.1.78 | Brucella sp. | P61711 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.5.1.78 | - |
Brucella sp. |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.5.1.78 | 5-amino-6-(1-D-ribitylamino)pyrimidine-2,4(1H,3H)-dione + (S)-2-hydroxy-3-oxobutyl dihydrogen phosphate | - |
Brucella sp. | 6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + 2 H2O | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.5.1.78 | ? | x * 18000, SDS-PAGE | Brucella sp. |
2.5.1.78 | More | Brucella spp. lumazine synthase arranges in icosahedric capsids similar to those formed by the lumazine synthases of other bacteria | Brucella sp. |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.5.1.78 | 37 | - |
assay at | Brucella sp. |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.5.1.78 | 7 | - |
assay at | Brucella sp. |