EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.4 | enteropeptidase | trypsinogen is activated through the cleavage of a peptide Val-Asp-Asp-Asp-Asp-Lys-Ile located on the N-terminus of the protein, the heptapetide is cleaved autocatalytically by its physiological activator, enteropeptidase | Bos taurus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.4 | HgCl2 | - |
Sesamia nonagrioides | |
3.4.21.4 | Lima bean trypsin inhibitor | - |
Rhynchophorus ferrugineus | |
3.4.21.4 | Lima bean trypsin inhibitor | - |
Sesamia nonagrioides | |
3.4.21.4 | phenylmethylsulfonyl fluoride | - |
Astacus astacus | |
3.4.21.4 | phenylmethylsulfonyl fluoride | - |
Penaeus japonicus | |
3.4.21.4 | phenylmethylsulfonyl fluoride | - |
Penaeus paulensis | |
3.4.21.4 | phenylmethylsulfonyl fluoride | - |
Rhynchophorus ferrugineus | |
3.4.21.4 | phenylmethylsulfonyl fluoride | - |
Rhyzopertha dominica | |
3.4.21.4 | phenylmethylsulfonyl fluoride | - |
Triatoma infestans | |
3.4.21.4 | Soybean trypsin inhibitor | - |
Penaeus japonicus | |
3.4.21.4 | Soybean trypsin inhibitor | - |
Rhynchophorus ferrugineus | |
3.4.21.4 | Soybean trypsin inhibitor | - |
Rhyzopertha dominica | |
3.4.21.4 | Soybean trypsin inhibitor | - |
Sesamia nonagrioides | |
3.4.21.4 | Soybean trypsin inhibitor | - |
Triatoma infestans | |
3.4.21.4 | tosyl-L-lysyl chloromethyl ketone | - |
Astacus astacus | |
3.4.21.4 | tosyl-L-lysyl chloromethyl ketone | - |
Penaeus japonicus | |
3.4.21.4 | tosyl-L-lysyl chloromethyl ketone | - |
Penaeus paulensis | |
3.4.21.4 | tosyl-L-lysyl chloromethyl ketone | - |
Rhyzopertha dominica | |
3.4.21.4 | tosyl-L-lysyl chloromethyl ketone | - |
Triops sp. | |
3.4.21.4 | trans-epoxysuccinyl-L-leucylamido-(4-guanidino) butane | - |
Rhyzopertha dominica | |
3.4.21.4 | trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane | - |
Sesamia nonagrioides |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.4 | additional information | not dependent on Ca2+ for activation or stability | Asterias amurensis | |
3.4.21.4 | additional information | not dependent on Ca2+ for activation or stability | Musca domestica | |
3.4.21.4 | additional information | not dependent on Ca2+ for activation or stability | Diatraea saccharalis |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.4.21.4 | 21700 | - |
- |
Penaeus paulensis |
3.4.21.4 | 24000 | - |
- |
Rhyzopertha dominica |
3.4.21.4 | 25000 | - |
- |
Astacus astacus |
3.4.21.4 | 25000 | - |
- |
Penaeus japonicus |
3.4.21.4 | 25000 | - |
- |
Manduca sexta |
3.4.21.4 | 26000 | - |
- |
Cancer pagurus |
3.4.21.4 | 26600 | - |
- |
Musca domestica |
3.4.21.4 | 28000 | - |
- |
Asterias amurensis |
3.4.21.4 | 28700 | - |
- |
Diatraea saccharalis |
3.4.21.4 | 31000 | - |
- |
Sesamia nonagrioides |
3.4.21.4 | 31000 | - |
- |
Triops sp. |
3.4.21.4 | 32000 | - |
- |
Penaeus vannamei |
3.4.21.4 | 40000 | - |
- |
Triatoma infestans |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.4 | Aedes aegypti | P29786 | - |
- |
3.4.21.4 | Astacus astacus | - |
- |
- |
3.4.21.4 | Asterias amurensis | - |
- |
- |
3.4.21.4 | Bos taurus | - |
- |
- |
3.4.21.4 | Cancer pagurus | - |
- |
- |
3.4.21.4 | Diaprepes abbreviatus | O76498 | Sugarcane rootstalk borer weevil | - |
3.4.21.4 | Diatraea saccharalis | - |
- |
- |
3.4.21.4 | Lepeophtheirus salmonis | Q7YSS9 | putative trypsin | - |
3.4.21.4 | Manduca sexta | P35045 | tobacco hornworm moth | - |
3.4.21.4 | Musca domestica | - |
- |
- |
3.4.21.4 | Penaeus japonicus | - |
- |
- |
3.4.21.4 | Penaeus paulensis | - |
- |
- |
3.4.21.4 | Penaeus vannamei | Q9TY16 | fragment; formerly Penaeus vannamei | - |
3.4.21.4 | Rhynchophorus ferrugineus | - |
red palm weevil | - |
3.4.21.4 | Rhyzopertha dominica | - |
- |
- |
3.4.21.4 | Sesamia nonagrioides | - |
- |
- |
3.4.21.4 | Stomoxys calcitrans | O76519 | - |
- |
3.4.21.4 | Stomoxys calcitrans | O76520 | - |
- |
3.4.21.4 | Triatoma infestans | - |
- |
- |
3.4.21.4 | Triops sp. | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.21.4 | animal | - |
Musca domestica | - |
3.4.21.4 | gastric juice | - |
Cancer pagurus | - |
3.4.21.4 | gut | - |
Rhynchophorus ferrugineus | - |
3.4.21.4 | hepatopancreas | - |
Astacus astacus | - |
3.4.21.4 | hepatopancreas | - |
Sesamia nonagrioides | - |
3.4.21.4 | hepatopancreas | - |
Rhyzopertha dominica | - |
3.4.21.4 | hepatopancreas | - |
Penaeus japonicus | - |
3.4.21.4 | hepatopancreas | - |
Penaeus paulensis | - |
3.4.21.4 | hepatopancreas | - |
Manduca sexta | - |
3.4.21.4 | hepatopancreas | - |
Penaeus vannamei | - |
3.4.21.4 | midgut | - |
Diatraea saccharalis | - |
3.4.21.4 | midgut | - |
Stomoxys calcitrans | - |
3.4.21.4 | pancreas | - |
Bos taurus | - |
3.4.21.4 | pyloric cecum | - |
Asterias amurensis | - |
3.4.21.4 | salivary gland | - |
Triatoma infestans | - |
3.4.21.4 | whole body | - |
Triops sp. | - |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.21.4 | midgut-specific serine protease 1 | - |
Stomoxys calcitrans |
3.4.21.4 | midgut-specific serine protease 2 | - |
Stomoxys calcitrans |
3.4.21.4 | trypsin 3A1 | - |
Aedes aegypti |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.4.21.4 | 7 | 8 | - |
Astacus astacus |
3.4.21.4 | 7 | 9.5 | - |
Rhyzopertha dominica |
3.4.21.4 | 8 | - |
- |
Asterias amurensis |
3.4.21.4 | 8 | - |
- |
Cancer pagurus |
3.4.21.4 | 8 | - |
- |
Triops sp. |
3.4.21.4 | 8 | 8.3 | - |
Penaeus japonicus |
3.4.21.4 | 8.5 | - |
- |
Musca domestica |
3.4.21.4 | 8.5 | 10.5 | - |
Sesamia nonagrioides |
3.4.21.4 | 9 | 10 | - |
Rhynchophorus ferrugineus |
3.4.21.4 | 10.5 | - |
- |
Diatraea saccharalis |
3.4.21.4 | 10.5 | - |
- |
Manduca sexta |