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Literature summary extracted from

  • Besnard, T.; Renee, N.; Etienne-Grimaldi, M.; Francois, E.; Milano, G.
    Optimized blood sampling with cytidine deaminase inhibitor for improved analysis of capecitabine metabolites (2008), J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 870, 117-120.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.4.5 tetrahydrouridine THU, the presence of 1 microM totally prevents the formation of 5'-deoxy-5-fluorouridine in blood samples of healthy volunteers and capecitabine-treated patients Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.4.5 cytidine + H2O Homo sapiens
-
 uridine + NH3
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.4.5 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.4.5 blood
-
 Homo sapiens
-
3.5.4.5 liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.4.5 5'-deoxyfluorocytidine + H2O
-
 Homo sapiens 5'-deoxy-5-fluorouridine + NH3
-
 ?
3.5.4.5 cytidine + H2O
-
 Homo sapiens uridine + NH3
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.4.5 CDA
-
 Homo sapiens
3.5.4.5 cytidine deaminase
-
 Homo sapiens