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Literature summary extracted from
- Active plasma kallikrein localizes to mast cells and regulates epithelial cell apoptosis, adipocyte differentiation and stromal remodeling during mammary gland involution (2009), J. Biol. Chem., 284, 13792-13803.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.34 | ecotin-plasma kallikrein | highly specific inhibitor of active plasma kallikrein | Mus musculus |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.4.21.34 | mast cell granule | - |
Mus musculus | 42629 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.34 | additional information | Mus musculus | active plasma kallikrein localizes to mast cells and regulates epithelial cell apoptosis, adipocyte differentiation and stromal remodeling during mammary gland involution | ? | - |
? |  |
| 3.4.21.34 | plasminogen + H2O | Mus musculus | - |
plasmin + ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.34 | Mus musculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.21.34 | mammary gland | mouse plasma kallikrein is differentially expressed in the developing mammary gland | Mus musculus | - |
| 3.4.21.34 | mast cell | active plasma kallikrein is localized to connective tissue-type mast cells in the mammary gland | Mus musculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.34 | additional information | active plasma kallikrein localizes to mast cells and regulates epithelial cell apoptosis, adipocyte differentiation and stromal remodeling during mammary gland involution | Mus musculus | ? | - |
? | |
| 3.4.21.34 | plasminogen + H2O | - |
Mus musculus | plasmin + ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.21.34 | PKal | - |
Mus musculus |
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