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Literature summary extracted from

  • Majumder, K.; Wu, J.
    Angiotensin I converting enzyme inhibitory peptides from simulated in vitro gastrointestinal digestion of cooked eggs (2009), J. Agric. Food Chem., 57, 471-477.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.15.1 L-Glu-L-Arg-L-Tyr-L-Pro-L-Ile
-
 Oryctolagus cuniculus
3.4.15.1 L-Ile-L-Pro-L-Phe
-
 Oryctolagus cuniculus
3.4.15.1 L-Leu-L-Pro-L-Phe
-
 Oryctolagus cuniculus
3.4.15.1 L-Met-L-Pro-L-Phe
-
 Oryctolagus cuniculus
3.4.15.1 L-Thr-L-Thr-L-Ile
-
 Oryctolagus cuniculus
3.4.15.1 L-Tyr-L-Thr-L-Ala-Gly-L-Val
-
 Oryctolagus cuniculus
3.4.15.1 L-Val-L-Asp-L-Phe
-
 Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.15.1 angiotensin I + H2O Oryctolagus cuniculus
-
 angiotensin II + L-His-L-Leu
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.15.1 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.15.1 lung
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.15.1 angiotensin I + H2O
-
 Oryctolagus cuniculus angiotensin II + L-His-L-Leu
-
 ?
3.4.15.1 hippuryl-L-His-L-Leu + H2O
-
 Oryctolagus cuniculus hippuric acid + L-His-L-Leu
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.15.1 ACE
-
 Oryctolagus cuniculus
3.4.15.1 angiotensin I converting enzyme
-
 Oryctolagus cuniculus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.4.15.1 0.00659
-
 in 100 mM potassium phosphate buffer containing 300 mM NaCl, at 37°C Oryctolagus cuniculus L-Val-L-Asp-L-Phe
3.4.15.1 0.00876
-
 in 100 mM potassium phosphate buffer containing 300 mM NaCl, at 37°C Oryctolagus cuniculus L-Glu-L-Arg-L-Tyr-L-Pro-L-Ile
3.4.15.1 0.00878
-
 in 100 mM potassium phosphate buffer containing 300 mM NaCl, at 37°C Oryctolagus cuniculus L-Ile-L-Pro-L-Phe
3.4.15.1 0.01059
-
 in 100 mM potassium phosphate buffer containing 300 mM NaCl, at 37°C Oryctolagus cuniculus L-Leu-L-Pro-L-Phe
3.4.15.1 0.01798
-
 in 100 mM potassium phosphate buffer containing 300 mM NaCl, at 37°C Oryctolagus cuniculus L-Met-L-Pro-L-Phe
3.4.15.1 0.02338
-
 in 100 mM potassium phosphate buffer containing 300 mM NaCl, at 37°C Oryctolagus cuniculus L-Tyr-L-Thr-L-Ala-Gly-L-Val
3.4.15.1 0.02494
-
 in 100 mM potassium phosphate buffer containing 300 mM NaCl, at 37°C Oryctolagus cuniculus L-Thr-L-Thr-L-Ile