Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Ahmed, A.M.; Shimamoto, T.
    Emergence of a cefepime- and cefpirome-resistant Citrobacter freundii clinical isolate harbouring a novel chromosomally encoded AmpC beta -lactamase, CMY-37 (2008), Int. J. Antimicrob. Agents, 32, 256-261.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.2.6 expressed in Escherichia coli TG1 Citrobacter freundii

Protein Variants

EC Number Protein Variants Comment Organism
3.5.2.6 L316I substitution is located within the R2 loop that is considered the hotspot region responsible for the extended substrate spectrum in class C beta-lactamases Citrobacter freundii

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.2.6 additional information Citrobacter freundii has a cefepime and cefpirome resistance Citrobacter freundii

Organism

EC Number Organism UniProt Comment Textmining
3.5.2.6 Citrobacter freundii
-
-
-
3.5.2.6 Citrobacter freundii 4306
-
-
-

Synonyms

EC Number Synonyms Comment Organism
3.5.2.6 AmpC
-
Citrobacter freundii
3.5.2.6 beta-lactamase
-
Citrobacter freundii
3.5.2.6 CMY-37
-
Citrobacter freundii

pI Value

EC Number Organism Comment pI Value Maximum pI Value
3.5.2.6 Citrobacter freundii about
-
9