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Literature summary extracted from

  • Secor, E.R.; Singh, A.; Guernsey, L.A.; McNamara, J.T.; Zhan, L.; Maulik, N.; Thrall, R.S.
    Bromelain treatment reduces CD25 expression on activated CD4+ T cells in vitro (2009), Int. Immunopharmacol., 9, 340-346.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.22.32 CD25 + H2O Ananas comosus bromelain proteolytically cleaved cell-surface CD25 from activated CD4+ T cells, a mechanism of action to exert therapeutic benefits in inflammatory conditions, overview ?
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3.4.22.32 additional information Ananas comosus CD4+ T cells retain the ability to divide after bromelain treatment ?
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Organism

EC Number Organism UniProt Comment Textmining
3.4.22.32 Ananas comosus
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.32 stem mature Ananas comosus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.32 CD25 + H2O bromelain proteolytically cleaved cell-surface CD25 from activated CD4+ T cells, a mechanism of action to exert therapeutic benefits in inflammatory conditions, overview Ananas comosus ?
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?
3.4.22.32 CD25 + H2O soluble CD25is a therapeutic target in inflammation, autoimmunity and allergy Ananas comosus ?
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?
3.4.22.32 additional information CD4+ T cells retain the ability to divide after bromelain treatment Ananas comosus ?
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?