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Literature summary extracted from

  • Dubois, V.; Lambeir, A.M.; Van der Veken, P.; Augustyns, K.; Creemers, J.; Chen, X.; Scharpe, S.; De Meester, I.
    Purification and characterization of dipeptidyl peptidase IV-like enzymes from bovine testes (2008), Front. Biosci., 13, 3558-3568.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.14.5 AB192 i.e. bis(4-acetamidophenyl) 1-((S)-prolyl)pyrrolidine-2(R,S)-phosphonate hydrochloride Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.14.5 glucagon-like peptide 1 + H2O Bos taurus
-
?
-
?
3.4.14.5 glucose-dependent insulinotropic polypeptide + H2O Bos taurus
-
?
-
?
3.4.14.5 neuropeptide Y + H2O Bos taurus
-
?
-
?
3.4.14.5 peptide YY + H2O Bos taurus
-
?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.4.14.5 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.14.5 DEAE Sepharose column chromatography Con A-Sepharose column chromatography, HiTrap nickel-chelating column chromatography, HiTrap phenyl column chromatography, ammonium sulfate precipitation, HiTrap Q column chromatography, Superdex 200 gel filtration, and Lys-isoindole affinity gel filtration Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.14.5 testis
-
Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.14.5 glucagon-like peptide 1 + H2O
-
Bos taurus ?
-
?
3.4.14.5 glucose-dependent insulinotropic polypeptide + H2O
-
Bos taurus ?
-
?
3.4.14.5 Gly-L-Pro-4-nitroanilide
-
Bos taurus Gly-L-Pro + 4-nitroaniline
-
?
3.4.14.5 L-Ala-L-Pro-4-nitroanilide
-
Bos taurus L-Ala-L-Pro + 4-nitroaniline
-
?
3.4.14.5 L-Arg-L-Pro-4-nitroanilide
-
Bos taurus L-Arg-L-Pro + 4-nitroaniline
-
?
3.4.14.5 neuropeptide Y + H2O
-
Bos taurus ?
-
?
3.4.14.5 peptide YY + H2O
-
Bos taurus ?
-
?

Synonyms

EC Number Synonyms Comment Organism
3.4.14.5 dipeptidyl peptidase-4
-
Bos taurus
3.4.14.5 DPPIV
-
Bos taurus