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Literature summary extracted from

  • Bunik, V.; Kaehne, T.; Degtyarev, D.; Shcherbakova, T.; Reiser, G.
    Novel isoenzyme of 2-oxoglutarate dehydrogenase is identified in brain, but not in heart (2008), FEBS J., 275, 4990-5006.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.4.2 mitochondrion
-
 Rattus norvegicus 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.2.4.2 117400
-
 calculated from amino acid sequence Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.2.4.2 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.4.2 poly(ethylene glycol) fractionation and Sephacryl HR300 gel filtration Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.4.2 brain isozyme 2-oxoglutarate dehydrogenase-like protein Rattus norvegicus
-
1.2.4.2 additional information 2-oxoglutarate dehydrogenase-like protein is not detected in heart Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.4.2 2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine
-
 Rattus norvegicus [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.4.2 2-oxoglutarate dehydrogenase first and rate-limiting component of the multienzyme 2-oxoglutarate dehydrogenase complex Rattus norvegicus
1.2.4.2 2-oxoglutarate dehydrogenase-like protein brain-specific isozyme Rattus norvegicus
1.2.4.2 E1o
-
 Rattus norvegicus
1.2.4.2 OGDH
-
 Rattus norvegicus
1.2.4.2 OGDHL brain-specific isozyme Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.4.2 NAD+
-
 Rattus norvegicus
1.2.4.2 thiamine diphosphate
-
 Rattus norvegicus