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Literature summary extracted from
- Increased expression of myo-inositol oxygenase is involved in the tubulointerstitial injury of diabetic nephropathy (2009), Exp. Clin. Endocrinol. Diabetes, 117, 257-265.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.13.99.1 | additional information | increased secretion in a dose-dependent manner after high-glucose treatment | Rattus norvegicus |
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.13.99.1 | transfection into NRK-52E cells | Rattus norvegicus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.13.99.1 | Rattus norvegicus | - |
control group and diabetes group | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.13.99.1 | renal cortex | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.13.99.1 | myo-inositol + O2 | - |
Rattus norvegicus | D-glucuronic acid + H2O | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.13.99.1 | MIOX | - |
Rattus norvegicus |
| 1.13.99.1 | Myo-inositol oxygenase | - |
Rattus norvegicus |
Expression
| EC Number | Organism | Comment | Expression |
|---|---|---|---|
| 1.13.99.1 | Rattus norvegicus | diabetic, nephropathy | up |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 1.13.99.1 | malfunction | increased expression in diabetic kidneys may contribute to tubulointerstitial injury and development of diabetic nephropathy | Rattus norvegicus |
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Release 2023.1 (January 2023)
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