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Literature summary extracted from

  • Kalme, S.; Pham, C.; Gedi, V.; Le, D.; Choi, J.; Kim, S.; Yoon, M.
    Inhibitors of Bacillus anthracis acetohydroxyacid synthase (2008), Enzyme Microb. Technol., 43, 270-275.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.2.1.6 chlorimuronethyl noncompetitive, lowest total interaction energy and highest MolDock score of 140054 kcal/mol and -141.52, respectively, of the compounds analyzed Bacillus anthracis
2.2.1.6 imazapyr
-
 Bacillus anthracis
2.2.1.6 imazaquin uncompetitive Bacillus anthracis
2.2.1.6 metsulfuronmethyl
-
 Bacillus anthracis
2.2.1.6 pyrazosulfuronethyl
-
 Bacillus anthracis
2.2.1.6 sulfometuronmethyl
-
 Bacillus anthracis
2.2.1.6 thifensulfuronmethyl
-
 Bacillus anthracis

Organism

EC Number Organism UniProt Comment Textmining
2.2.1.6 Bacillus anthracis
-
-
-

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
2.2.1.6 0.00697
-
 37°C Bacillus anthracis imazaquin
2.2.1.6 0.007
-
 37°C Bacillus anthracis chlorimuronethyl
2.2.1.6 0.01
-
 37°C Bacillus anthracis sulfometuronmethyl