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Literature summary extracted from

  • Seo, H.; Kim, M.; Choi, Y.; Lee, C.K.; Ka, H.
    Analysis of lysophosphatidic acid (LPA) receptor and LPA-induced endometrial prostaglandin-endoperoxide synthase 2 expression in the porcine uterus (2008), Endocrinology, 149, 6166-6175.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
1.14.99.1 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.99.1 uterine endometrium
-
Sus scrofa
-
1.14.99.1 uterus
-
Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.99.1 arachidonate + AH2 + O2
-
Sus scrofa prostaglandin H2 + A + H2O
-
?

Synonyms

EC Number Synonyms Comment Organism
1.14.99.1 cyclooxygenase 2
-
Sus scrofa
1.14.99.1 PG G/H synthase 2
-
Sus scrofa
1.14.99.1 prostaglandin-endoperoxide synthase 2
-
Sus scrofa
1.14.99.1 PTGS2
-
Sus scrofa

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.99.1 heme
-
Sus scrofa

Expression

EC Number Organism Comment Expression
1.14.99.1 Sus scrofa 0.1 and 0.001 mM lysophosphatidic acid increases PTGS2 mRNA abundance in the uterine endometrium, the lysophosphatidic acid-induced increase of PTGS2 expression is reduced by cotreatment with Ki-16425 up