EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.146 | PF-877423 | specific 11beta-HSD1 inhibitor | Homo sapiens | |
1.1.1.146 | PF-877423 | specific 11beta-HSD1 inhibitor | Mus musculus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.146 | Homo sapiens | - |
- |
- |
1.1.1.146 | Mus musculus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.146 | pancreatic islet | 11beta-HSD1 co-localises with glucagon in the periphery of pancreatic islets, but not with insulin or somatostatin | Mus musculus | - |
1.1.1.146 | pancreatic islet | 11beta-HSD1 co-localises with glucagon in the periphery of pancreatic islets, but not with insulin or somatostatin | Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.146 | 11-dehydrocorticosterone + NADPH | - |
Mus musculus | corticosterone + NADP+ | - |
? | |
1.1.1.146 | 11-dehydrocorticosterone + NADPH | - |
Homo sapiens | corticosterone + NADP+ | - |
? | |
1.1.1.146 | cortisone + NADPH + H+ | - |
Mus musculus | cortisol + NADP+ | - |
? | |
1.1.1.146 | cortisone + NADPH + H+ | - |
Homo sapiens | cortisol + NADP+ | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.1.1.146 | 11beta-HSD1 | - |
Mus musculus |
1.1.1.146 | 11beta-HSD1 | - |
Homo sapiens |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase type 1 | - |
Mus musculus |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase type 1 | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.146 | NADPH | - |
Mus musculus | |
1.1.1.146 | NADPH | - |
Homo sapiens |