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Literature summary extracted from

  • Morikawa, T.; Xie, H.; Wang, T.; Matsuda, H.; Yoshikawa, M.
    Bioactive constituents from Chinese natural medicines. XXXII. aminopeptidase N and aldose reductase inhibitors from Sinocrassula indica: structures of sinocrassosides B4, B5, C1, and D1-D3 (2008), Chem. Pharm. Bull., 56, 1438-1444.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.2 curcumin 31.9% inhibition at 0.03 mM Homo sapiens
3.4.11.2 kaempferol 13.7% inhibition at 0.03 mM Homo sapiens
3.4.11.2 kaempferol 3-O-beta -D-glucopyranosyl-(1-'4)-a -L-rhamnopyranosyl-7-O-alpha -L-rhamnopyranoside 13.8% inhibition at 0.03 mM Homo sapiens
3.4.11.2 kaempferol 3-O-beta-D-glucopyranoside 31.7% inhibition at 0.03 mM Homo sapiens
3.4.11.2 kaempferol 3-O-beta-D-glucopyranosyl-7-O-alpha-L-rhamnopyranoside 19.1% inhibition at 0.03 mM Homo sapiens
3.4.11.2 kaempferol 7-O-alpha-L-rhamnopyranoside 12.5% inhibition at 0.03 mM Homo sapiens
3.4.11.2 luteolin 60.2% inhibition at 0.03 mM Homo sapiens
3.4.11.2 additional information not inhibited by trans-(3S,5R,6R,9S)-megastigman-7-ene-3,5,6,9-tetraol 3-O-glucoside and trans-(3S,5R,6R,9S)-megastigman-7-ene-3,5,6,9-tetraol 9-O-glucoside Homo sapiens
3.4.11.2 multiflorin B 32.8% inhibition at 0.03 mM Homo sapiens
3.4.11.2 multinoside A 15.3% inhibition at 0.03 mM Homo sapiens
3.4.11.2 quercetin 18.1% inhibition at 0.03 mM Homo sapiens
3.4.11.2 quercetin 3-O-glucoside 41.8% inhibition at 0.03 mM Homo sapiens
3.4.11.2 quercetin-3-O-beta-D-glucopyranosyl-7-O-alpha-L-rhamnopyranoside 12.6% inhibition at 0.03 mM Homo sapiens
3.4.11.2 sinocrassoside A1 31.4% inhibition at 0.03 mM Homo sapiens
3.4.11.2 sinocrassoside A10 28.7% inhibition at 0.03 mM Homo sapiens
3.4.11.2 sinocrassoside A2 35.7% inhibition at 0.03 mM Homo sapiens
3.4.11.2 sinocrassoside A4 26.9% inhibition at 0.03 mM Homo sapiens
3.4.11.2 sinocrassoside A5 21.7% inhibition at 0.03 mM Homo sapiens
3.4.11.2 sinocrassoside A6 16.4% inhibition at 0.03 mM Homo sapiens
3.4.11.2 sinocrassoside A7 23.7% inhibition at 0.03 mM Homo sapiens
3.4.11.2 sinocrassoside A9 19.9% inhibition at 0.03 mM Homo sapiens
3.4.11.2 sinocrassoside B1 33.9% inhibition at 0.03 mM Homo sapiens
3.4.11.2 sinocrassoside B2 39.4% inhibition at 0.03 mM Homo sapiens
3.4.11.2 sinocrassoside B3 36.2% inhibition at 0.03 mM Homo sapiens
3.4.11.2 sinocrassoside B4 32.1% inhibition at 0.03 mM Homo sapiens
3.4.11.2 sinocrassoside B5 28.3% inhibition at 0.03 mM Homo sapiens
3.4.11.2 sinocrassoside C1 12.4% inhibition at 0.03 mM Homo sapiens
3.4.11.2 sinocrassoside D1 35.1% inhibition at 0.03 mM Homo sapiens
3.4.11.2 sinocrassoside D3 23.2% inhibition at 0.03 mM Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.2 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.2 L-Ala-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens L-Ala + 7-amino-4-methylcoumarin
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.11.2 alanine aminopeptidase
-
 Homo sapiens
3.4.11.2 aminopeptidase N
-
 Homo sapiens
3.4.11.2 APN
-
 Homo sapiens