EC Number | Application | Comment | Organism |
---|---|---|---|
1.2.1.41 | medicine | in humans a natural S352L mutation gives rise to type II hyperprolinemia, mental retardation | Thermus thermophilus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.1.41 | L-glutamate 5-semialdehyde + phosphate + NAD+ | Thermus thermophilus | - |
L-glutamyl 5-phosphate + NADH + H+ | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.2.1.41 | Thermus thermophilus | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.1.41 | L-glutamate 5-semialdehyde + phosphate + NAD+ | - |
Thermus thermophilus | L-glutamyl 5-phosphate + NADH + H+ | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.2.1.41 | hexamer | composed by dimers | Thermus thermophilus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.2.1.41 | ALDH4 | - |
Thermus thermophilus |
1.2.1.41 | gamma glutamyl semialdehyde dehydrogenase | - |
Thermus thermophilus |
1.2.1.41 | GGSALDH | - |
Thermus thermophilus |
1.2.1.41 | pyrroline 5-carboxylate dehydrogenase | - |
Thermus thermophilus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.2.1.41 | NAD+ | the work based on a computer simulation using a PDB data set of Thermus thermophilus GGSALDH, pdb2BJA, in this structure the enzyme is co-crystallized with NADH | Thermus thermophilus |