Literature summary extracted from

Lyon, R.C.; Johnston, S.M.; Panopoulos, A.; Alzeer, S.; McGarvie, G.; Ellis, E.M.
Enzymes involved in the metabolism of gamma-hydroxybutyrate in SH-SY5Y cells: identification of an iron-dependent alcohol dehydrogenase ADHFe1 (2009), Chem. Biol. Interact., 178, 283-287.

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.99.24	Homo sapiens	Q8IWW8	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.1.99.24	SH-SY5Y cell	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.99.24	4-hydroxybutanoic acid + 2-oxoglutarate	-	Homo sapiens	succinic semialdehyde + D-2-hydroxyglutarate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.1.99.24	hydroxyacid-oxoacid transhydrogenase	-	Homo sapiens
1.1.99.24	iron-dependent alcohol dehydrogenase ADHFe1	-	Homo sapiens

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.1.99.24	NAD(P)+	2-oxoglutarate serves as an intermediate acceptor to generate NAD(P)H	Homo sapiens

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Release 2023.1 (January 2023)