BRENDA - Enzyme Database

Alternate AChE-R variants facilitate cellular metabolic activity and resistance to genotoxic stress through enolase and RACK1 interactions

Mor, I.; Bruck, T.; Greenberg, D.; Berson, A.; Schreiber, L.; Grisaru, D.; Soreq, H.; Chem. Biol. Interact. 175, 11-21 (2008)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
4.2.1.11
acetylcholinesterase C-terminal peptide ARP
the 26-amino-acid-long acetylcholinesterase C-terminal peptide ARP elevates activity of enolase in dose-dependent manner: 200 nM ARP by 7.1%, 600 nM ARP by 12.5%
Oryctolagus cuniculus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.2.1.11
Oryctolagus cuniculus
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
4.2.1.11
-
Oryctolagus cuniculus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
4.2.1.11
muscle
-
Oryctolagus cuniculus
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
4.2.1.11
additional information
-
31.2 nmol 2-PGA converted/min/36nM enolase
Oryctolagus cuniculus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.11
2-phospho-D-glycerate
-
697260
Oryctolagus cuniculus
phosphoenolpyruvate + H2O
-
-
-
r
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
4.2.1.11
acetylcholinesterase C-terminal peptide ARP
the 26-amino-acid-long acetylcholinesterase C-terminal peptide ARP elevates activity of enolase in dose-dependent manner: 200 nM ARP by 7.1%, 600 nM ARP by 12.5%
Oryctolagus cuniculus
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
4.2.1.11
-
Oryctolagus cuniculus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
4.2.1.11
muscle
-
Oryctolagus cuniculus
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
4.2.1.11
additional information
-
31.2 nmol 2-PGA converted/min/36nM enolase
Oryctolagus cuniculus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.11
2-phospho-D-glycerate
-
697260
Oryctolagus cuniculus
phosphoenolpyruvate + H2O
-
-
-
r