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Literature summary extracted from

  • Morikawa, T.; Xie, H.; Wang, T.; Matsuda, H.; Yoshikawa, M.
    Acylated flavonol bisdesmosides, sinocrassosides A3-A7 and B3, with aminopeptidase N inhibitory activity from Sinocrassula indica (2009), Chem. Biodivers., 6, 411-420.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.2 curcumin 31.9% inhibition at 0.03 mM Homo sapiens
3.4.11.2 kaempferol 3-O-beta-D-(3''-acetylglucopyranosyl)-7-O-alpha-L-2'''-O-[(S)-2-methylbutanoyl]rhamnopyranoside 16.4% inhibition at 0.03 mM Homo sapiens
3.4.11.2 kaempferol 3-O-beta-D-(3''-O-acetylglucopyranocyl)-7-O-alpha-L-3'''-O-[(S)-2-methylbutanoyl]rhamnopyranoside 23.7% inhibition at 0.03 mM Homo sapiens
3.4.11.2 kaempferol 3-O-beta-D-(3''-O-acetylglucopyranosyl)-7-O-alpha-L-(2'''-O-isobutyryl)rhamnopyranoside 21.7% inhibition at 0.03 mM Homo sapiens
3.4.11.2 kaempferol 3-O-beta-D-glucopyranosyl-7-O-(3''-O-isobutyryl)rhamnopyranoside 26.9% inhibition at 0.03 mM Homo sapiens
3.4.11.2 quercetin 3-O-beta-D-glucopyranosyl-7-O-alpha-L-3'''-O-[(2S)-2-methylbutanoyl]-rhamnopyranoside 36.2% inhibition at 0.03 mM Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.11.2 Zn2+ dependent on Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.2 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.2 L-Ala-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens L-Ala + 7-amino-4-methylcoumarin
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.11.2 aminopeptidase N
-
 Homo sapiens
3.4.11.2 APN
-
 Homo sapiens