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Literature summary extracted from

  • Calvin, K.; Li, H.
    RNA-splicing endonuclease structure and function (2008), Cell. Mol. Life Sci., 65, 1176-1185.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.6.1.16 tRNA + H2O Saccharomyces cerevisiae The enzyme is responsible for the excision of introns from nuclear transfer RNA (tRNA) and all archaeal RNAs. tRNA containing 5'hydroxy and 2',3'-cyclic phosphate termini
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Organism

EC Number Organism UniProt Comment Textmining
4.6.1.16 Saccharomyces cerevisiae
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.16 tRNA + H2O The enzyme is responsible for the excision of introns from nuclear transfer RNA (tRNA) and all archaeal RNAs. Saccharomyces cerevisiae tRNA containing 5'hydroxy and 2',3'-cyclic phosphate termini
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?

Subunits

EC Number Subunits Comment Organism
4.6.1.16 tetramer four different subunits alpha, beta, gamma, delta Saccharomyces cerevisiae

Synonyms

EC Number Synonyms Comment Organism
4.6.1.16 RNA-splicing endonuclease
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Saccharomyces cerevisiae