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Literature summary extracted from

  • Liu, H.W.; Cheng, B.; Li, J.F.; Wu, H.J.; Li, K.Y.; Sun, T.Z.; Fu, X.B.
    Characterization of angiotensin-converting enzyme expression during epidermis morphogenesis in humans: a potential marker for epidermal stem cells (2009), Br. J. Dermatol., 160, 250-258.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.15.1 angiotensin I + H2O Homo sapiens
-
angiotensin II + L-His-L-Leu
-
?
3.4.15.1 additional information Homo sapiens ACE may play a role in human epidermis morphogenesis during fetal life and serve as an unrecognized marker for keratinocyte progenitor cells ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.4.15.1 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.15.1 epidermis at 11-13 weeks of gestation ACE-positive cells are observed in the primitive epidermis, as the fetuses develops ACE-positive cells appear in all the epidermal layers, and from 21 weeks of gestation ACE expression is largely restricted to the basal layer of the fetal epidermis, while ACE-positive cells are found only in the adult skin basal layer which harbours epidermal stem cells Homo sapiens
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3.4.15.1 skin fetal skin Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.15.1 angiotensin I + H2O
-
Homo sapiens angiotensin II + L-His-L-Leu
-
?
3.4.15.1 additional information ACE may play a role in human epidermis morphogenesis during fetal life and serve as an unrecognized marker for keratinocyte progenitor cells Homo sapiens ?
-
?

Synonyms

EC Number Synonyms Comment Organism
3.4.15.1 ACE
-
Homo sapiens
3.4.15.1 angiotensin-converting enzyme
-
Homo sapiens