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Literature summary extracted from

  • Mirabelli, P.; Di Noto, R.; Lo Pardo, C.; Morabito, P.; Abate, G.; Gorrese, M.; Raia, M.; Pascariello, C.; Scalia, G.; Gemei, M.; Mariotti, E.; Del Vecchio, L.
    Extended flow cytometry characterization of normal bone marrow progenitor cells by simultaneous detection of aldehyde dehydrogenase and early hematopoietic antigens: implication for erythroid differentiation studies (2008), BMC Physiol., 8, 13.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
1.2.1.3 medicine findings are useful for basic studies about normal erythropoietic differentiation as well as for enabling the employment of ALDH as a red cell marker in polychromatic flow cytometry characterization of bone marrow from patients with aplastic anemia and myelodysplasia Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.3 4-diethylaminobenzaldehyde DEAB Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.3 cytosol
-
Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.3 an aldehyde + NAD+ + H2O Homo sapiens
-
an acid + NADH + H+
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.3 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.3 bone marrow
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.3 an aldehyde + NAD+ + H2O
-
Homo sapiens an acid + NADH + H+
-
?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.3 aldehyde dehydrogenase
-
Homo sapiens
1.2.1.3 ALDH
-
Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.3 NAD+
-
Homo sapiens