Literature summary extracted from

Curti, A.; Trabanelli, S.; Salvestrini, V.; Baccarani, M.; Lemoli, R.M.
The role of indoleamine 2,3-dioxygenase in the induction of immune tolerance: focus on hematology (2009), Blood, 113, 2394-2401.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.13.11.52	1-Methyltryptophan	-	Homo sapiens
1.13.11.52	brassinin	-	Homo sapiens
1.13.11.52	methyl-thiohydantoin tryptophan	-	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.13.11.52	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.13.11.52	mesenchymal stem cell	-	Homo sapiens	-
1.13.11.52	myeloid leukemia cell	-	Homo sapiens	-
1.13.11.52	regulatory dendritic cell	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.13.11.52	L-tryptophan + O2	-	Homo sapiens	N-formylkynurenine	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.13.11.52	indoleamine 2,3-dioxygenase	-	Homo sapiens

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.13.11.52	heme	-	Homo sapiens

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Release 2023.1 (January 2023)