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Literature summary extracted from
- Oviductal microsomal epoxide hydrolase (EPHX1) reduces reactive oxygen species (ROS) level and enhances preimplantation mouse embryo development (2009), Biol. Reprod., 81, 126-132.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.3.2.9 | 1,1,1-Trichloropropene 2,3-oxide | - |
Homo sapiens |  |
| 3.3.2.9 | 1,1,1-Trichloropropene 2,3-oxide | - |
Mus musculus | |
| 3.3.2.9 | Cyclohexene oxide | - |
Homo sapiens | |
| 3.3.2.9 | Cyclohexene oxide | - |
Mus musculus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.3.2.9 | microsome | - |
Mus musculus | - |
- |
| 3.3.2.9 | microsome | - |
Homo sapiens | - |
- |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.3.2.9 | additional information | Homo sapiens | EPHX1 detoxifies genotoxic compounds and participates in the removal of reactive oxygen species | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.3.2.9 | Homo sapiens | - |
- |
- |
| 3.3.2.9 | Mus musculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.3.2.9 | OE-E6/E7 cell | - |
Homo sapiens | - |
| 3.3.2.9 | oviduct | - |
Homo sapiens | - |
| 3.3.2.9 | oviduct | the transcript of Ephx1 increases in the oviductal epithelium at the estrus stage and in day 3 of pregnancy | Mus musculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.3.2.9 | cis-stilbene oxide + H2O | - |
Mus musculus | (1R,2R)-1,2-diphenylethane-1,2-diol | - |
? | |
| 3.3.2.9 | cis-stilbene oxide + H2O | - |
Homo sapiens | (1R,2R)-1,2-diphenylethane-1,2-diol | - |
? | |
| 3.3.2.9 | additional information | EPHX1 detoxifies genotoxic compounds and participates in the removal of reactive oxygen species | Homo sapiens | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.3.2.9 | EPHX1 | - |
Homo sapiens |
| 3.3.2.9 | EPHX1 | EPHX1 detoxifies genotoxic compounds and participates in the removal of reactive oxygen species | Mus musculus |
| 3.3.2.9 | mEH | - |
Mus musculus |
| 3.3.2.9 | mEH | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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