EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.22.48 | additional information | immunglobulin G and immunglobulin G's Fc fragment reduce the effect of SspB | Staphylococcus aureus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.22.48 | Staphylococcus aureus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
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EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.4.22.48 | additional information | - |
peripheral blood neutrophils and monocytes exposed to SspB are extensively phagocytosed by resting human monocyte-derived macrophages in a time- and concentration-dependent manner. SspB-treated neutrophils engulfed in phagosomesstill preserve mitochondrial potential. SspB blocks phagocytosis of opsonised Staphylococcus aureus by neutrophils and monocytes. SspB blocks the chemotactic activity of neutrophils. SspB decreases surface expression of the major repulsion signal CD31 on neutrophils both in the absence and presence of human serum. | Staphylococcus aureus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.22.48 | SspB | - |
Staphylococcus aureus |
3.4.22.48 | staphopain B | - |
Staphylococcus aureus |