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Literature summary extracted from

  • Olgun, A.
    Converting NADH to NAD+ by nicotinamide nucleotide transhydrogenase as a novel strategy against mitochondrial pathologies during aging (2009), Biogerontology, 10, 531-534.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.6.1.2 additional information NNT expression is 2.8fold downregulated in the vastus lateralis muscle of calorie restricted rhesus monkeys Macaca mulatta

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.6.1.2 mitochondrial inner membrane
-
 Mus musculus 5743
-
1.6.1.2 mitochondrial inner membrane
-
 Caenorhabditis elegans 5743
-
1.6.1.2 mitochondrial inner membrane
-
 Macaca mulatta 5743
-

Organism

EC Number Organism UniProt Comment Textmining
1.6.1.2 Caenorhabditis elegans
-
-
-
1.6.1.2 Macaca mulatta
-
-
-
1.6.1.2 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.6.1.2 muscle
-
 Macaca mulatta
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.6.1.2 NADP+ + NADH
-
 Mus musculus NADPH + NAD+
-
 r
1.6.1.2 NADP+ + NADH
-
 Caenorhabditis elegans NADPH + NAD+
-
 r
1.6.1.2 NADP+ + NADH
-
 Macaca mulatta NADPH + NAD+
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.6.1.2 nicotinamide nucleotide transhydrogenase
-
 Mus musculus
1.6.1.2 nicotinamide nucleotide transhydrogenase
-
 Caenorhabditis elegans
1.6.1.2 nicotinamide nucleotide transhydrogenase
-
 Macaca mulatta
1.6.1.2 NNT
-
 Mus musculus
1.6.1.2 NNT
-
 Caenorhabditis elegans
1.6.1.2 NNT
-
 Macaca mulatta